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Uncomfortable feet fatigue, pain and swelling usually appears during long trips, when there is a lot of walking also while taking long flight or sitting at work. Dry and less oxygenated air in the airplane, thickens the blood, which is a major risk factor for blood clots. Low mobility and prolonged sitting with bent knees also contribute to thrombus formation. In order to avoid the risk of frustrating leg pain, swelling and thrombus formation, it is recommended to wear travel compression socks which ensure the closing of the vein valves and the efficient blood return from the feet to the heart.